Now, it’s Jerod Mayo as the Patriots’ head coach with rookie Drake Maye at quarterback facing Justin Herbert and Chargers coach Jim Harbaugh. Kick-off is at 1 p.m. ET on Saturday.

The New England Patriots will face the Buffalo Bills in week 16 of the NFL season at Highmark Stadium on Sunday, December 22nd. WATCH: Patriots vs Bills Live | Stream free on Fubo New England will receive one of the top picks in the 2025 NFL Draft,

The loss moved New England (3-12) into position for the No. 2 pick in the 2025 NFL Draft, something the Patriots will likely maintain with losses in the final games against Los Angeles and Buffalo. Wins in either contest would likely drop New England several spots in the draft order.

Kickoff for the Patriots game against the Bills will be at 4:25 p.m. (EST) on Sunday, Dec. 22. The Patriots will be playing in Highmark Stadium in Orchard Park, New York. The current forecast calls for very sunny conditions but also the coldest of the winter so far with a high of 18, according to AccuWeather.

The New England Patriots (3-11) and the Buffalo Bills (11-3) meet Sunday in a Week 16 game at Highmark Stadium. Kickoff is scheduled for 4:25 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's

The Buffalo Bills (11-3) host a struggling New England Patriots (3-11) team on Sunday, Dec. 22, 2024 at Highmark Stadium. The Patriots have lost four straight games. Date: Dec. 22 Time: 4:25 p.m. ET Over their last five meetings, Buffalo has tallied four wins versus New England.

TL;DR: Live stream New England Patriots vs. Buffalo Bills on YouTube TV or Paramount+. NFL Week 16 action continues with the New England Patriots playing the Buffalo Bills. The Patriots are having a rough season and are currently at the bottom of AFC East ...

Looking at Sunday’s New England Patriots at Buffalo Bills Week 16 NFL odds, lines and trends. Here’s what you need to know.

The Buffalo Bills (11-3) are home at Highmark Stadium to take on division rival New England Patriots (3-11) at 4:25 p.m. Follow here for live updates throughout the game.

The New England Patriots are expected to retain Jerod Mayo as the head coach going into the 2025 season, according to NFL insider Ian Rapoport. Mayo has struggled in his first season as head coach with the Patriots.