In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for ...

In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the ...

Researchers find that a gene linked to Alzheimer's triggers inflammation in healthy brain immune cells, offering new insights ...

Reducing microglial activity in the presence of apolipoprotein E4 (APOE4) has uncovered a mechanism associated with the deposition of misfolded amyloid and tau in a novel mouse model of Alzheimer’s ...

apoER2 (apolipoprotein E receptor-2) is a transmembrane receptor in the low-density ... the apoER2 R952Q variant and increased atherosclerosis risk. An apoER2 R952Q mouse model was generated using a ...

SORL1 knockout, knockin, and transgenic mice are now in the Research Models database. The database will be updated as more models become available.

Whether you're after a comfortable all-in-one powerhouse or a flyweight pointer for fps, a Razer mouse can set you on a solid path to victory. These rodents come from a pedigree line of gaming ...

Nik Dennler does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.